Selective Ablation of Ppp1cc Gene in Testicular Germ Cells Causes Oligo-Teratozoospermia and Infertility in Mice1
نویسندگان
چکیده
منابع مشابه
Lack of testicular seipin causes teratozoospermia syndrome in men.
Obesity impairs male fertility, providing evidence for a link between adipose tissue and reproductive function; however, potential consequences of adipose tissue paucity on fertility remain unknown. Lack of s.c. fat is a hallmark of Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), which is caused by mutations in BSCL2-encoding seipin. Mice with a targeted deletion of murine seipin mod...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2013
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.113.110239